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Mutations reveal voltage gating of CNGA1 channels in saturating cGMP

Activity of cyclic nucleotide–gated (CNG) cation channels underlies signal transduction in vertebrate visual receptors. These highly specialized receptor channels open when they bind cyclic GMP (cGMP). Here, we find that certain mutations restricted to the region around the ion selectivity filter re...

詳細記述

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書誌詳細
主要な著者: Martínez-François, Juan Ramón, Xu, Yanping, Lu, Zhe
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717697/
https://ncbi.nlm.nih.gov/pubmed/19635856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200910240
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