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Extracellular protons titrate voltage gating of a ligand-gated ion channel

Cyclic nucleotide–gated channels mediate transduction of light into electric signals in vertebrate photoreceptors. These channels are primarily controlled by the binding of intracellular cyclic GMP (cGMP). Glutamate residue 363 near the extracellular end of the ion selectivity filter interacts with...

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Bibliografiske detaljer
Main Authors: Martínez-François, Juan Ramón, Xu, Yanping, Lu, Zhe
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912074/
https://ncbi.nlm.nih.gov/pubmed/20624857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201010444
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