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Extracellular protons titrate voltage gating of a ligand-gated ion channel

Cyclic nucleotide–gated channels mediate transduction of light into electric signals in vertebrate photoreceptors. These channels are primarily controlled by the binding of intracellular cyclic GMP (cGMP). Glutamate residue 363 near the extracellular end of the ion selectivity filter interacts with...

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Autores principales: Martínez-François, Juan Ramón, Xu, Yanping, Lu, Zhe
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912074/
https://ncbi.nlm.nih.gov/pubmed/20624857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201010444
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