Functional Enhancers at the Gene-Poor 8q24 Cancer-Linked Locus

Multiple discrete regions at 8q24 were recently shown to contain alleles that predispose to many cancers including prostate, breast, and colon. These regions are far from any annotated gene and their biological activities have been unknown. Here we profiled a 5-megabase chromatin segment encompassin...

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Detalhes bibliográficos
Main Authors: Jia, Li, Landan, Gilad, Pomerantz, Mark, Jaschek, Rami, Herman, Paula, Reich, David, Yan, Chunli, Khalid, Omar, Kantoff, Phil, Oh, William, Manak, J. Robert, Berman, Benjamin P., Henderson, Brian E., Frenkel, Baruch, Haiman, Christopher A., Freedman, Matthew, Tanay, Amos, Coetzee, Gerhard A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717370/
https://ncbi.nlm.nih.gov/pubmed/19680443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000597
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