FcεRI -INDUCED ACTIVATION BY LOW ANTIGEN CONCENTRATIONS RESULTS IN NUCLEAR SIGNALS IN THE ABSENCE OF DEGRANULATION

High affinity IgE receptor (FcεRI)-induced activation of mast cells results in degranulation and generation of leukotrienes and cytokines. FcεRI-induced mast cell activation was analyzed at a single cell basis using a rat basophilic leukemia (RBL-2H3) cell line transfected with a reporter plasmid co...

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Bibliographic Details
Main Authors: Grodzki, Ana Cristina G., Moon, Kyungduk D., Berenstein, Elsa H., Siraganian, Reuben P.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717025/
https://ncbi.nlm.nih.gov/pubmed/19540596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2009.05.013
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