Involvement of Bruton's Tyrosine Kinase in FcεRI-dependent Mast Cell Degranulation and Cytokine Production

We investigated the role of Bruton's tyrosine kinase (Btk) in FcεRI-dependent activation of mouse mast cells, using xid and btk null mutant mice. Unlike B cell development, mast cell development is apparently normal in these btk mutant mice. However, mast cells derived from these mice exhibited...

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Detalhes bibliográficos
Main Authors: Hata, Daisuke, Kawakami, Yuko, Inagaki, Naoki, Lantz, Chris S., Kitamura, Toshio, Khan, Wasif N., Maeda-Yamamoto, Mari, Miura, Toru, Han, Wei, Hartman, Stephen E., Yao, Libo, Nagai, Hiroichi, Goldfeld, Anne E., Alt, Frederick W., Galli, Stephen J., Witte, Owen N., Kawakami, Toshiaki
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212237/
https://ncbi.nlm.nih.gov/pubmed/9547335
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