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The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters

Certain proteins contain subunits that enable their active translocation across the plasma membrane into cells. In the specific case of HIV-1, this subunit is the basic domain Tat(49–57) (RKKRRQRRR). To establish the optimal structural requirements for this translocation process, and thereby to deve...

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Autori principali: Wender, Paul A., Mitchell, Dennis J., Pattabiraman, Kanaka, Pelkey, Erin T., Steinman, Lawrence, Rothbard, Jonathan B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC27168/
https://ncbi.nlm.nih.gov/pubmed/11087855
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