Overexpression of Rhodopsin Alters the Structure and Photoresponse of Rod Photoreceptors

Rhodopsins are densely packed in rod outer-segment membranes to maximize photon absorption, but this arrangement interferes with transducin activation by restricting the mobility of both proteins. We attempted to explore this phenomenon in transgenic mice that overexpressed rhodopsin in their rods....

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Detaylı Bibliyografya
Asıl Yazarlar: Wen, Xiao-Hong, Shen, Lixin, Brush, Richard S., Michaud, Norman, Al-Ubaidi, Muayyad R., Gurevich, Vsevolod V., Hamm, Heidi E., Lem, Janis, DiBenedetto, Emmanuele, Anderson, Robert E., Makino, Clint L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Biophysical Society 2009
Konular:
Channels, Receptors, and Electrical Signaling
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716671/
https://ncbi.nlm.nih.gov/pubmed/19186132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.10.016
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