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Loop Dynamics of the Extracellular Domain of Human Tissue Factor and Activation of Factor VIIa
In the crystal structure of the complex between the soluble extracellular domain of tissue factor (sTF) and active-site-inhibited VIIa, residues 91 and 92 in the Pro(79)-Pro(92) loop of sTF interact with the catalytic domain of VIIa. It is not known, however, whether this loop has a role in alloster...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2716462/ https://ncbi.nlm.nih.gov/pubmed/19167313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.10.018 |
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