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Kinetic Study of β-Amyloid residue accessibility using Reductive Alkylation and Mass Spectrometry
Beta-amyloid peptide (Aβ) is the major protein constituent found in senile plaques in Alzheimer's disease (AD). It is believed that Aβ plays a role in neurodegeneration associated with AD and that its toxicity is related to its structure or aggregation state. In this study, an approach based on...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2716430/ https://ncbi.nlm.nih.gov/pubmed/19418563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.22367 |
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