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MdmX regulates transformation and chromosomal stability in p53-deficient cells

The cellular homologues Mdm2 and MdmX play critical roles in regulating the activity of the p53 tumor suppressor in damaged and non-damaged cells and during development in mice. Recently, we have utilized genetically defined primary cells and mice to reveal that endogenous levels of MdmX can also su...

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Hlavní autoři: Matijasevic, Zdenka, Krzywicka-Racka, Anna, Sluder, Greenfield, Jones, Stephen N.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716213/
https://ncbi.nlm.nih.gov/pubmed/18818521
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