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Superoxide-mediated inactivation of nitric oxide and peroxynitrite formation by tobacco smoke in vascular endothelium: studies in cultured cells and smokers

Tobacco smoke is known to cause nitric oxide ((·)NO) inactivation and endothelial dysfunction. In this work we evaluated the interplay between (·)NO and superoxide (O(2)(·−)) radicals and the consequent impact on (·)NO bioavailability and nitroxidative stress in bovine aortic endothelial cells expos...

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Bibliografische gegevens
Hoofdauteurs: Peluffo, Gonzalo, Calcerrada, Pablo, Piacenza, Lucia, Pizzano, Nelson, Radi, Rafael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716106/
https://ncbi.nlm.nih.gov/pubmed/19363134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00930.2008
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