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Metabolism and regulation of canonical histone mRNAs: life without a poly(A) tail
The canonical histone proteins are encoded by replication-dependent genes and must rapidly reach high levels of expression during S phase. In metazoans the genes that encode these proteins produce mRNAs that, instead of being polyadenylated, contain a unique 3' end structure. By contrast, the s...
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Main Authors: | , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2008
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2715827/ https://ncbi.nlm.nih.gov/pubmed/18927579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg2438 |
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