Prions Are Secreted in Milk from Clinically Normal Scrapie-Exposed Sheep

The potential spread of prion infectivity in secreta is a crucial concern for prion disease transmission. Here, serial protein misfolding cyclic amplification (sPMCA) allowed the detection of prions in milk from clinically affected animals as well as scrapie-exposed sheep at least 20 months before c...

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Detalhes bibliográficos
Main Authors: Maddison, B. C., Baker, C. A., Rees, H. C., Terry, L. A., Thorne, L., Bellworthy, S. J., Whitelam, G. C., Gough, K. C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715765/
https://ncbi.nlm.nih.gov/pubmed/19494004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00051-09
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