Heterosexual Transmission of Human Immunodeficiency Virus Type 1 Subtype C: Macrophage Tropism, Alternative Coreceptor Use, and the Molecular Anatomy of CCR5 Utilization

Human immunodeficiency virus type 1 transmission selects for virus variants with genetic characteristics distinct from those of donor quasispecies, but the biological factors favoring their transmission or establishment in new hosts are poorly understood. We compared primary target cell tropisms and...

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Hlavní autoři: Isaacman-Beck, Jesse, Hermann, Emilia A., Yi, Yanjie, Ratcliffe, Sarah J., Mulenga, Joseph, Allen, Susan, Hunter, Eric, Derdeyn, Cynthia A., Collman, Ronald G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715751/
https://ncbi.nlm.nih.gov/pubmed/19515785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00296-09
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