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Human Immunodeficiency Virus Type 1 IIIB Selected for Replication In Vivo Exhibits Increased Envelope Glycoproteins in Virions without Alteration in Coreceptor Usage: Separation of In Vivo Replication from Macrophage Tropism

Analysis of viral replication and pathogenicity after in vivo selection of human immunodeficiency virus type 1 (HIV-1) attenuated in vitro will help to define the functions involved in replication and pathogenesis in vivo. Using the SCID-hu Thy/Liv mouse and human fetal thymus organ culture as in vi...

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Bibliographic Details
Main Authors: Miller, Eric D., Duus, Karen M., Townsend, Michael, Yi, Yanjie, Collman, Ronald, Reitz, Marvin, Su, Lishan
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC115095/
https://ncbi.nlm.nih.gov/pubmed/11507195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.18.8498-8506.2001
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