Prediction of HIV-1 Coreceptor Usage (Tropism) by Sequence Analysis using a Genotypic Approach

Maraviroc (MVC) is the first licensed antiretroviral drug from the class of coreceptor antagonists. It binds to the host coreceptor CCR5, which is used by the majority of HIV strains in order to infect the human immune cells (Fig. 1). Other HIV isolates use a different coreceptor, the CXCR4. Which r...

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Detalhes bibliográficos
Main Authors: Sierra, Saleta, Kaiser, Rolf, Lübke, Nadine, Thielen, Alexander, Schuelter, Eugen, Heger, Eva, Däumer, Martin, Reuter, Stefan, Esser, Stefan, Fätkenheuer, Gerd, Pfister, Herbert, Oette, Mark, Lengauer, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2011
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369655/
https://ncbi.nlm.nih.gov/pubmed/22157596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/3264
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