Prediction of HIV-1 Coreceptor Usage (Tropism) by Sequence Analysis using a Genotypic Approach

Maraviroc (MVC) is the first licensed antiretroviral drug from the class of coreceptor antagonists. It binds to the host coreceptor CCR5, which is used by the majority of HIV strains in order to infect the human immune cells (Fig. 1). Other HIV isolates use a different coreceptor, the CXCR4. Which r...

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Bibliografische gegevens
Hoofdauteurs: Sierra, Saleta, Kaiser, Rolf, Lübke, Nadine, Thielen, Alexander, Schuelter, Eugen, Heger, Eva, Däumer, Martin, Reuter, Stefan, Esser, Stefan, Fätkenheuer, Gerd, Pfister, Herbert, Oette, Mark, Lengauer, Thomas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MyJove Corporation 2011
Onderwerpen:
Immunology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369655/
https://ncbi.nlm.nih.gov/pubmed/22157596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/3264
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