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Entry coreceptor use and fusion inhibitor T20 sensitivity of dual-tropic R5X4 HIV-1 in primary macrophage infection
Macrophages are important targets for HIV-1 and R5X4 strains play a central role in pathogenesis, especially in late-stage patients who may receive the fusion inhibitor T20. Sensitivity to T20 varies markedly among HIV-1 strains and is influenced by both viral and cellular factors that affect Env/CD...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2769518/ https://ncbi.nlm.nih.gov/pubmed/18197116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e31816520f6 |
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