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Entry coreceptor use and fusion inhibitor T20 sensitivity of dual-tropic R5X4 HIV-1 in primary macrophage infection

Macrophages are important targets for HIV-1 and R5X4 strains play a central role in pathogenesis, especially in late-stage patients who may receive the fusion inhibitor T20. Sensitivity to T20 varies markedly among HIV-1 strains and is influenced by both viral and cellular factors that affect Env/CD...

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Sonraí Bibleagrafaíochta
Main Authors: Yi, Yanjie, Loftin, Lamorris, Wang, Lingshu, Ratcliffe, Sarah J., Isaacman-Beck, Jesse, Collman, Ronald G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2769518/
https://ncbi.nlm.nih.gov/pubmed/18197116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e31816520f6
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