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Ultradeep Pyrosequencing Detects Complex Patterns of CD8(+) T-Lymphocyte Escape in Simian Immunodeficiency Virus-Infected Macaques
Human and simian immunodeficiency viruses (HIV/SIV) exhibit enormous sequence heterogeneity within each infected host. Here, we use ultradeep pyrosequencing to create a comprehensive picture of CD8(+) T-lymphocyte (CD8-TL) escape in SIV-infected macaques, revealing a previously undetected complex pa...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2715741/ https://ncbi.nlm.nih.gov/pubmed/19515775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00897-09 |
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