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Unique Roles of DosT and DosS in DosR Regulon Induction and Mycobacterium tuberculosis Dormancy

In Mycobacterium tuberculosis, the sensor kinases DosT and DosS activate the transcriptional regulator DosR, resulting in the induction of the DosR regulon, which is important for anaerobic survival and perhaps latent infection. The individual and collective roles of these sensors have been postulat...

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Detalles Bibliográficos
Autores principales: Honaker, Ryan W., Leistikow, Rachel L., Bartek, Iona L., Voskuil, Martin I.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715697/
https://ncbi.nlm.nih.gov/pubmed/19487478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01449-08
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