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Unique Roles of DosT and DosS in DosR Regulon Induction and Mycobacterium tuberculosis Dormancy

In Mycobacterium tuberculosis, the sensor kinases DosT and DosS activate the transcriptional regulator DosR, resulting in the induction of the DosR regulon, which is important for anaerobic survival and perhaps latent infection. The individual and collective roles of these sensors have been postulat...

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Detalhes bibliográficos
Main Authors: Honaker, Ryan W., Leistikow, Rachel L., Bartek, Iona L., Voskuil, Martin I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715697/
https://ncbi.nlm.nih.gov/pubmed/19487478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01449-08
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