Efficacy of Liposomal Amphotericin B Combined with Gamma Interferon or Granulocyte-Macrophage Colony-Stimulating Factor for Treatment of Systemic Zygomycosis in Mice

Granulocyte-macrophage colony-stimulating factor enhanced the efficacy of liposomal amphotericin B (LAMB) in a murine model of disseminated infection by Rhizopus oryzae, significantly prolonging survival and reducing tissue burden. The use of gamma interferon (IFN-γ) alone was ineffective, and IFN-γ...

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Bibliographische Detailangaben
Hauptverfasser: Rodríguez, M. Mar, Calvo, Enrique, Mariné, Marçal, Pastor, F. Javier, Fernandez-Ballart, Joan, Guarro, Josep
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2009
Schlagworte:
Experimental Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715637/
https://ncbi.nlm.nih.gov/pubmed/19451289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00456-09
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