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Design of therapeutic proteins with enhanced stability
Therapeutic proteins such as antibodies constitute the most rapidly growing class of pharmaceuticals for use in diverse clinical settings including cancer, chronic inflammatory diseases, kidney transplantation, cardiovascular medicine, and infectious diseases. Unfortunately, they tend to aggregate w...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2715526/ https://ncbi.nlm.nih.gov/pubmed/19571001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904191106 |
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