Polysialic acid governs T-cell development by regulating progenitor access to the thymus

Although the polysialyltransferase ST8Sia IV is expressed in both primary and secondary human lymphoid organs, its product, polysialic acid (polySia), has been largely overlooked by immunologists. In contrast, polySia expression and function in the nervous system has been well characterized. In this...

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Main Authors: Drake, Penelope M., Stock, Christina M., Nathan, Jay K., Gip, Phung, Golden, Kevin P. K., Weinhold, Birgit, Gerardy-Schahn, Rita, Bertozzi, Carolyn R.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2009
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715481/
https://ncbi.nlm.nih.gov/pubmed/19587240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905188106
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