Polysialic acid governs T-cell development by regulating progenitor access to the thymus

Although the polysialyltransferase ST8Sia IV is expressed in both primary and secondary human lymphoid organs, its product, polysialic acid (polySia), has been largely overlooked by immunologists. In contrast, polySia expression and function in the nervous system has been well characterized. In this...

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Detalhes bibliográficos
Main Authors: Drake, Penelope M., Stock, Christina M., Nathan, Jay K., Gip, Phung, Golden, Kevin P. K., Weinhold, Birgit, Gerardy-Schahn, Rita, Bertozzi, Carolyn R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715481/
https://ncbi.nlm.nih.gov/pubmed/19587240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905188106
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