Polysialic acid governs T-cell development by regulating progenitor access to the thymus

Although the polysialyltransferase ST8Sia IV is expressed in both primary and secondary human lymphoid organs, its product, polysialic acid (polySia), has been largely overlooked by immunologists. In contrast, polySia expression and function in the nervous system has been well characterized. In this...

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Bibliographic Details
Main Authors: Drake, Penelope M., Stock, Christina M., Nathan, Jay K., Gip, Phung, Golden, Kevin P. K., Weinhold, Birgit, Gerardy-Schahn, Rita, Bertozzi, Carolyn R.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715481/
https://ncbi.nlm.nih.gov/pubmed/19587240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905188106
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