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Cytokine-Induced Endothelial Arginase Expression Is Dependent on Epidermal Growth Factor Receptor
L-arginine is metabolized to nitric oxide (NO) by NO synthase (NOS), or to urea and L-ornithine by arginase. L-ornithine contributes to vascular remodeling in pulmonary hypertension via metabolism to polyamines and proline. Previously we found that cytokines upregulate both NOS and arginase in pulmo...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Thoracic Society
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2715346/ https://ncbi.nlm.nih.gov/pubmed/15994432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2005-0039OC |
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