Proteinase-Activated Receptor-1 Mediates Elastase-Induced Apoptosis of Human Lung Epithelial Cells

Apoptosis of distal lung epithelial cells plays a pivotal role in the pathogenesis of acute lung injury. In this context, proteinases, either circulating or leukocyte-derived, may contribute to epithelial apoptosis and lung injury. We hypothesized that apoptosis of lung epithelial cells induced by l...

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Detalhes bibliográficos
Main Authors: Suzuki, Tomoko, Moraes, Theo J., Vachon, Eric, Ginzberg, Hedy H., Huang, Tsun-Tsao, Matthay, Michael A., Hollenberg, Morley D., Marshall, John, McCulloch, Christopher A. G., Abreu, Maria Teresa Herrera, Chow, Chung-Wai, Downey, Gregory P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715314/
https://ncbi.nlm.nih.gov/pubmed/15891109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2005-0109OC
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