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Interferon-γ-Jak-Stat Signaling in Pulmonary Lymphangioleiomyomatosis and Renal Angiomyolipoma: A Potential Therapeutic Target

Pulmonary lymphangioleiomyomatosis (LAM) and renal angiomyolipoma (AML) are proliferative lesions that occur in sporadic patients, and at much higher frequency in patients with tuberous sclerosis (TSC). The TSC1 and TSC2 genes play a critical role in their pathogenesis. Here we report a marked decre...

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Detalhes bibliográficos
Main Authors: El-Hashemite, Nisreen, Kwiatkowski, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715313/
https://ncbi.nlm.nih.gov/pubmed/15994429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2005-0152RC
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