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Interferon-γ-Jak-Stat Signaling in Pulmonary Lymphangioleiomyomatosis and Renal Angiomyolipoma: A Potential Therapeutic Target

Pulmonary lymphangioleiomyomatosis (LAM) and renal angiomyolipoma (AML) are proliferative lesions that occur in sporadic patients, and at much higher frequency in patients with tuberous sclerosis (TSC). The TSC1 and TSC2 genes play a critical role in their pathogenesis. Here we report a marked decre...

詳細記述

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書誌詳細
主要な著者: El-Hashemite, Nisreen, Kwiatkowski, David J.
フォーマット: Artigo
言語:Inglês
出版事項: American Thoracic Society 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715313/
https://ncbi.nlm.nih.gov/pubmed/15994429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2005-0152RC
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