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Arf6 and microtubules in adhesion-dependent trafficking of lipid rafts

Integrin-mediated adhesion regulates Rac1 membrane binding sites within lipid rafts. Detachment of cells from the substratum triggers clearance of rafts from the plasma membrane through caveolin-dependent internalization. The small GTPase Arf6 and microtubules also regulate Rac-dependent cell spread...

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Detalhes bibliográficos
Main Authors: Balasubramanian, Nagaraj, Scott, David W., Castle, J. David, Casanova, James E., Schwartz, Martin Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715295/
https://ncbi.nlm.nih.gov/pubmed/18026091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1657
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