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Nucleolin-Mediated Cellular Trafficking of DNA Nanoparticle Is Lipid Raft and Microtubule Dependent and Can Be Modulated by Glucocorticoid

DNA nanoparticles (DNPs) are nonviral gene transfer vectors with excellent in vivo potential. Previously, we reported that cell surface nucleolin directly binds DNPs, and functions as an important receptor for DNPs. However, the fate of the nucleolin–DNP complex following cellular uptake remains elu...

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Bibliografische gegevens
Hoofdauteurs: Chen, Xuguang, Shank, Samuel, Davis, Pamela B, Ziady, Assem G
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017445/
https://ncbi.nlm.nih.gov/pubmed/20959809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.214
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