Loss of GATA4 and GATA6 Expression Specifies Ovarian Cancer Histological Subtypes and Precedes Neoplastic Transformation of Ovarian Surface Epithelia

BACKGROUND: The family of zinc finger-containing GATA transcription factors plays critical roles in cell lineage specification during early embryonic development and organ formation. GATA4 and GATA6 were found to be frequently lost in ovarian cancer, and the loss is proposed to account for dediffere...

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Main Authors: Cai, Kathy Qi, Caslini, Corrado, Capo-chichi, Callinice D., Slater, Carolyn, Smith, Elizabeth R., Wu, Hong, Klein-Szanto, Andres J., Godwin, Andrew K., Xu, Xiang-Xi
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2009
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715102/
https://ncbi.nlm.nih.gov/pubmed/19649254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006454
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