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Overexpression and cytoplasmic localization of caspase-6 is associated with lamin A degradation in set of ovarian cancers

BACKGROUND: In most women with ovarian cancer, the diagnosis occurs after dissemination of tumor cells beyond ovaries. Several molecular perturbations occur ahead of tumor initiation including loss of lamin A/C. Our hypothesis was that the loss of nuclear structural proteins A type lamins (lamin A/C...

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Publicado en:Biomark Res
Main Authors: Capo-chichi, Callinice D, Cai, Kathy Q, Xu, Xiang-Xi
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208109/
https://ncbi.nlm.nih.gov/pubmed/30450209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40364-018-0144-9
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