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Histone modifications silence the GATA transcription factor genes in ovarian cancer
Altered expression of GATA factors was found and proposed as the underlying mechanism for dedifferentiation in ovarian carcinogenesis. In particular, GATA6 is lost or excluded from the nucleus in 85% of ovarian tumors and GATA4 expression is absent in majority of ovarian cancer cell lines. Here, we...
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| Publicado no: | Oncogene |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7523731/ https://ncbi.nlm.nih.gov/pubmed/16607277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1209533 |
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