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Antigen-presenting cells containing multiple costimulatory molecules promote activation and expansion of antigen-specific memory CD8(+) T cells
We have previously demonstrated that multiple immunizations with vector-based vaccines containing transgenes for tumor Ags and a triad of costimulatory molecules (TRICOM) enhance the expansion and functional avidity of Ag-specific memory CD8(+) T cells in a mouse model. However, the effect of enhanc...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2714549/ https://ncbi.nlm.nih.gov/pubmed/18690438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-008-0572-8 |
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