Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications

The APOBEC family members are involved in diverse biological functions. APOBEC3G restricts the replication of human immunodeficiency virus (HIV), hepatitis B virus and retroelements by cytidine deamination on single-stranded DNA or by RNA binding1–4. Here we report the high-resolution crystal struct...

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Bibliografske podrobnosti
Main Authors: Holden, Lauren G., Prochnow, Courtney, Chang, Y. Paul, Bransteitter, Ronda, Chelico, Linda, Sen, Udayaditya, Stevens, Raymond C., Goodman, Myron F., Chen, Xiaojiang S.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714533/
https://ncbi.nlm.nih.gov/pubmed/18849968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07357
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