A diaryl sulfide, sulfoxide, and sulfone bearing structural similarities to combretastatin A-4

Studies examining various spacer groups that link the two aromatic rings of combretastatin A-4 (CA4) have shown that the biological activity of analogs does not require the cis-stilbene configuration of CA4. Oxygen or nitrogen, carbonyl, methylene and ethylene spacers, for example, are present in CA...

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Main Authors: Barbosa, Euzébio G., Bega, Luis A.S., Beatriz, Adilson, Sarkar, Taradas, Hamel, Ernest, do Amaral, Marcos S., de Lima, Dênis Pires
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714051/
https://ncbi.nlm.nih.gov/pubmed/19135763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2008.12.018
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