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Activator protein 2α suppresses intestinal tumorigenesis in the Apc(min) mouse

Activator protein 2α (AP-2α) is a putative tumor suppressor, and various reports have described the loss or reduction of AP-2α expression in cutaneous malignant melanomas, as well as in cancers of the prostate, breast and colon. Previously, AP-2α was shown to attenuate β-catenin/T-cell factor-4 (TCF...

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Bibliographic Details
Main Authors: Li, Qingjie, Löhr, Christiane V., Dashwood, Roderick H.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713803/
https://ncbi.nlm.nih.gov/pubmed/19376641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2009.03.026
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