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Expression of COX-2, NF-κB-p65, NF-κB-p50 and IKKα in malignant and adjacent normal human colorectal tissue

BACKGROUND: Cyclooxygenase-2 (COX-2) is selectively over-expressed in colorectal tumours. The mechanism of COX-2 induction in these tumours is not fully understood, although evidence suggests a possible link between nuclear factor (NF)-κB and COX-2. We hypothesised an association between COX-2 expre...

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Detalhes bibliográficos
Main Authors: Charalambous, M P, Lightfoot, T, Speirs, V, Horgan, K, Gooderham, N J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713702/
https://ncbi.nlm.nih.gov/pubmed/19513071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605120
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