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IKK-β/NFκB p65 Mediates p27(kip1) Protein Degradation in Arsenite Response
p27(kip1) is a potent inhibitor of the cyclin-dependent kinases that drive G1 to S phase transition. Since deregulation of p27(kip1) is found in many malignancies and is associated with the poor prognosis, elucidation of the molecular bases for regulation of p27(kip1) expression is of great signific...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4076889/ https://ncbi.nlm.nih.gov/pubmed/24751519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.04.055 |
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