Circulating Fibroblast Growth Factor-21 Is Elevated in Impaired Glucose Tolerance and Type 2 Diabetes and Correlates With Muscle and Hepatic Insulin Resistance

OBJECTIVE: Fibroblast growth factor (FGF)-21 is highly expressed in the liver and regulates hepatic glucose production and lipid metabolism in rodents. However, its role in the pathogenesis of type 2 diabetes in humans remains to be defined. The aim of this study was to quantitate circulating plasma...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Chavez, Alberto O., Molina-Carrion, Marjorie, Abdul-Ghani, Muhammad A., Folli, Franco, DeFronzo, Ralph A., Tripathy, Devjit
التنسيق: Artigo
اللغة:Inglês
منشور في: American Diabetes Association 2009
الموضوعات:
Original Research
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713625/
https://ncbi.nlm.nih.gov/pubmed/19487637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc09-0684
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