Multipotent adult progenitor cells can suppress graft-versus-host disease via prostaglandin E(2) synthesis and only if localized to sites of allopriming

Multipotent adult progenitor cells (MAPCs) are nonhematopoietic stem cells capable of giving rise to a broad range of tissue cells. As such, MAPCs hold promise for tissue injury repair after transplant. In vitro, MAPCs potently suppressed allogeneic T-cell activation and proliferation in a dose-depe...

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Main Authors: Highfill, Steven L., Kelly, Ryan M., O'Shaughnessy, Matthew J., Zhou, Qing, Xia, Lily, Panoskaltsis-Mortari, Angela, Taylor, Patricia A., Tolar, Jakub, Blazar, Bruce R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2009
Assuntos:
Transplantation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713464/
https://ncbi.nlm.nih.gov/pubmed/19458354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-03-213850
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