Venom factor V from the common brown snake escapes hemostatic regulation through procoagulant adaptations

Venomous snakes produce an array of toxic compounds, including procoagulants to defend themselves and incapacitate prey. The Australian snake Pseudonaja textilis has a venom-derived prothrombin activator homologous to coagulation factors V (FV) and Xa (FXa). Here we show that the FV component (pt-FV...

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Autors principals: Bos, Mettine H. A., Boltz, Michael, St. Pierre, Liam, Masci, Paul P., de Jersey, John, Lavin, Martin F., Camire, Rodney M.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2009
Matèries:
Thrombosis and Hemostasis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713460/
https://ncbi.nlm.nih.gov/pubmed/19365080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-02-202663
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