טוען...
Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibition
Inhibitors of apoptosis (IAPs) inhibit caspases, thereby preventing proteolysis of apoptotic substrates. IAPs occlude the active sites of caspases to which they are bound1-3 and can function as ubiquitin ligases. IAPs are also reported to ubiquitinate themselves and caspases4,5. Several proteins ind...
שמור ב:
| Main Authors: | , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2002
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2713440/ https://ncbi.nlm.nih.gov/pubmed/12021770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb798 |
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