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Lasting Reduction of Cocaine Action in Neostriatum— A Hydrolase Gene Therapy Approach
We previously found that a quadruple mutant cocaine hydrolase derived from human butyrylcholinesterase [termed cocaine esterase (CocE)] can suppress or reverse cocaine toxicity and abolish drug-primed reinstatement in rats. Here, we examined whether gene transfer of CocE reduces cocaine actions in b...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Pharmacology and Experimental Therapeutics
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2713082/ https://ncbi.nlm.nih.gov/pubmed/19478136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.152231 |
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