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Intracellular calcium strongly potentiates agonist-activated TRPC5 channels

TRPC5 is a calcium (Ca(2+))-permeable nonselective cation channel expressed in several brain regions, including the hippocampus, cerebellum, and amygdala. Although TRPC5 is activated by receptors coupled to phospholipase C, the precise signaling pathway and modulatory signals remain poorly defined....

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Detalhes bibliográficos
Main Authors: Blair, Nathaniel T., Kaczmarek, J. Stefan, Clapham, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712973/
https://ncbi.nlm.nih.gov/pubmed/19398778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200810153
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