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Calpain cleaves and activates the TRPC5 channel to participate in semaphorin 3A-induced neuronal growth cone collapse

The nonselective cation channel transient receptor potential canonical (TRPC)5 is found predominantly in the brain and has been proposed to regulate neuronal processes and growth cones. Here, we demonstrate that semaphorin 3A-mediated growth cone collapse is reduced in hippocampal neurons from TRPC5...

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Detalhes bibliográficos
Main Authors: Kaczmarek, J. Stefan, Riccio, Antonio, Clapham, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356680/
https://ncbi.nlm.nih.gov/pubmed/22547824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205869109
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