Individual Stearoyl-CoA Desaturase 1 Expression Modulates Endoplasmic Reticulum Stress and Inflammation in Human Myotubes and Is Associated With Skeletal Muscle Lipid Storage and Insulin Sensitivity In Vivo

OBJECTIVE: Increased plasma levels of free fatty acids occur in obesity and type 2 diabetes and contribute to the development of insulin resistance. Saturated fatty acids (SFAs) such as palmitate especially have lipotoxic effects leading to endoplasmatic reticulum (ER) stress, inflammation, and insu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Peter, Andreas, Weigert, Cora, Staiger, Harald, Machicao, Fausto, Schick, Fritz, Machann, Jürgen, Stefan, Norbert, Thamer, Claus, Häring, Hans-Ulrich, Schleicher, Erwin
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2009
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712792/
https://ncbi.nlm.nih.gov/pubmed/19478146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0188
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados