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Interpreting a Low Resolution Map of Human U1 snRNP Using Anomalous Scatterers

We recently determined the crystal structure of the functional core of human U1 snRNP, consisting of nine proteins and one RNA, based on a 5.5 Å resolution electron density map. At 5–7 Å resolution, α helices and β sheets appear as rods and slabs, respectively, hence it is not possible to determine...

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Main Authors: Oubridge, Chris, Krummel, Daniel A. Pomeranz, Leung, Adelaine K.-W., Li, Jade, Nagai, Kiyoshi
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2009
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712673/
https://ncbi.nlm.nih.gov/pubmed/19604473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.05.009
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