Aβ Oligomers and Fibrillar Aggregates Induce Different Apoptotic Pathways in LAN5 Neuroblastoma Cell Cultures

Fibril deposit formation of amyloid β-protein (Aβ) in the brain is a hallmark of Alzheimer's disease (AD). Increasing evidence suggests that toxicity is linked to diffusible Aβ oligomers, which have been found in soluble brain extracts of AD patients, rather than to insoluble fibers. Here we re...

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Detaylı Bibliyografya
Asıl Yazarlar: Picone, Pasquale, Carrotta, Rita, Montana, Giovanna, Nobile, Maria Rita, San Biagio, Pier Luigi, Di Carlo, Marta
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Biophysical Society 2009
Konular:
Protein
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712196/
https://ncbi.nlm.nih.gov/pubmed/19450490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.11.056
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